Cochrane | Trusted evidence. Informed decisions. Better health.
Cochrane helps launch new WHO guidance on best practices for clinical trials. 8 October 2024. News. Cochrane Ireland and Cochrane Crowd empower citizen scientists in The People’s Review. 16 October 2024. News. World EBHC Day 2024 underscores the need for greater intersectoral collaboration to build resilient evidence ecosystems. 16 October 2024.
Does adding fluoride to water supplies prevent tooth decay?
Fluoride is a mineral which occurs naturally in water at different concentrations. It prevents tooth decay. Since 1975, fluoride has been an ingredient in most toothpastes. It is available in some mouth-rinses, and dentists use treatments that contain fluoride. It is possible to add fluoride to the local water supply.
Oral painkillers available without prescription for acute pain
Non-prescription (over-the-counter, or OTC) analgesics (painkillers) are used frequently. They are available in various brands, package sizes, formulations, and dose. They can be used for a range of different types of pain, but this overview reports on how well they work for acute pain (pain of short duration, usually with rapid onset).
Duloxetine for treating painful neuropathy, chronic pain or
Duloxetine at 60 mg daily is effective in treating painful diabetic peripheral neuropathy in the short term, with a risk ratio (RR) for ≥ 50% pain reduction at 12 weeks of 1.73 (95% CI 1.44 to 2.08). The related NNTB is 5 (95% CI 4 to 7). Duloxetine at 60 mg daily is also effective for fibromyalgia over 12 weeks (RR for ≥ 50% reduction in ...
How accurate are rapid antigen tests for diagnosing COVID-19?
Accurate rapid diagnostic tests for SARS-CoV-2 infection would be a useful tool to help manage the COVID-19 pandemic. Testing strategies that use rapid antigen tests to detect current infection have the potential to increase access to testing, speed detection of infection, and inform clinical and public health management decisions to reduce transmission.
What are the benefits and risks of vaccines for preventing COVID …
Dec 7, 2022 · Key messages. – Most vaccines reduce, or probably reduce, the number of people who get COVID-19 disease and severe COVID-19 disease. – Many vaccines likely increase number of people experiencing events such as fever or headache compared to placebo (sham vaccine that contains no medicine but looks identical to the vaccine being tested).
In women who have had one or both breasts removed, which …
5 days ago · Key messages • Breast reconstruction surgery that uses autologous tissue (the woman's own tissue, like fat or muscle) rather than implants might lead to better mental and sexual well-being and greater satisfaction with the operation overall.
Strategies for managing sexual dysfunction caused by ... - Cochrane
A wide range of management strategies are possible to address this problem, including behavioural, psychological and pharmacological approaches. 1. To determine the effectiveness of management strategies for sexual dysfunction caused by antidepressants. 2. To determine the adverse effects and acceptability of the different management strategies.
About us - Cochrane
Cochrane is for anyone interested in using high-quality information to make health decisions. Whether you are a clinician, patient or carer, researcher, or policy-maker, Cochrane evidence provides a powerful tool to enhance your healthcare knowledge and decision-making. Cochrane's members and supporters come from more than 190 countries, worldwide.
Stopping blood pressure medications in older people | Cochrane
People in the studies had an average age of 58 to 82 years. In three of the studies, the dose of the antihypertensive was slowly lowered before stopping. Key results. We found that stopping antihypertensive medications is possible in older adults. Most of the older people in the discontinuation groups did not need to restart their medication.