RNA silencing - Wikipedia
WEBRNA silencing or RNA interference refers to a family of gene silencing effects by which gene expression is negatively regulated by non-coding RNAs such as microRNAs. RNA silencing may also be defined as sequence-specific regulation of gene expression triggered by double-stranded RNA (dsRNA). [1]
RNA Interference: Biology, Mechanism, and Applications
WEBDouble-stranded RNA-mediated interference (RNAi) is a simple and rapid method of silencing gene expression in a range of organisms. The silencing of a gene is a consequence of degradation of RNA into short RNAs that activate ribonucleases to target homologous mRNA.
RNA silencing: From discovery and elucidation to application ...
WEBRNA silencing (or RNA interference, RNAi) is a conserved mechanism for regulating gene expression in eukaryotes. The discovery of natural trans-kingdom RNAi indicated that small RNAs act as signaling molecules and enable communication between organisms in different kingdoms.
RNA silencing in plants - Nature
WEBSep 15, 2004 · There are at least three RNA silencing pathways for silencing specific genes in plants. In these pathways, silencing signals can be amplified and transmitted between cells, and may even be...
RNA Silencing - an overview | ScienceDirect Topics
WEBRNA silencing is a type of gene regulation that, in plants, serves as an antiviral defense. RNA silencing is based on targeting specific sequences of RNA and degrading them. RNA silencing occurs in a broad range of eukaryotic organisms, including plants, …
RNA Silencing in Plants: Mechanisms, Technologies and ...
WEBRNA silencing is an evolutionarily conserved mechanism in eukaryotes. It is induced by double-stranded RNA (dsRNA) or hairpin structured RNA (hpRNA), involving common factors including Dicer or Dicer-like (DCL) and Argonaute (AGO) family proteins [1 - 3].
Roles of RNA silencing in viral and non-viral plant immunity ...
WEBJun 16, 2022 · RNA silencing is a well-established antiviral immunity system in plants, in which small RNAs guide Argonaute proteins to targets in viral RNA or DNA, resulting in virus repression....
Mechanisms of gene silencing by double-stranded RNA - Nature
WEBSep 15, 2004 · A key step in known silencing pathways is the processing of dsRNAs into short RNA duplexes of characteristic size and structure. These short dsRNAs guide RNA silencing by specific and distinct...
Molecular Mechanisms and Biological Functions of siRNA
WEBMar 30, 2017 · siRNA mediate silencing of target genes by guiding sequence dependent slicing of their target mRNAs. These non-coding, silencing RNAs begin as long dsRNA molecules, which are processed by endonuclease Dicer into short, active ~21-25 …
RNA: Guiding Gene Silencing | Science - AAAS
WEBAug 10, 2001 · Here we adopt a broad definition of RNA silencing that encompasses effects in the cytoplasm and the nucleus, and consider their possible developmental roles and evolutionary origins.