Brain tumor vaccine: Experimental shot shows promise against glioblastoma
An experimental brain cancer vaccine improved survival time in patients with glioblastoma, the deadliest type of brain tumor. The vaccine, called SurVaxM, was shown to nearly double the survival...
‘Dramatic’ inroads against aggressive brain cancer - Harvard Gazette
Mar 14, 2024 · In a paper published Wednesday in The New England Journal of Medicine, researchers from Mass General Cancer Center shared the results for the first three patient cases from a Phase 1 clinical trial evaluating a new approach to CAR-T therapy for glioblastoma.
UF-developed mRNA vaccine triggers fierce immune response to …
May 1, 2024 · In a first-ever human clinical trial of four adult patients, an mRNA cancer vaccine developed at the University of Florida quickly reprogrammed the immune system to attack glioblastoma, the most aggressive and lethal brain tumor.
Breakthrough Therapy Obliterates Deadly Brain Tumor in Days
Mar 15, 2024 · Brain scans of a 72-year-old man diagnosed with a highly aggressive form of cancer known as a glioblastoma have revealed a remarkable regression in his tumor's size within days of receiving an infusion of an innovative new treatment.
New glioblastoma treatment reaches human brain tumor and …
Jun 6, 2024 · In a major advance for the treatment of the deadly brain cancer glioblastoma, scientists used ultrasound technology to penetrate the blood-brain barrier and provide a small dose of a chemotherapy...
Glioblastoma: Why immunotherapy may offer hope for brain …
1 day ago · Glioblastoma is a naturally occurring tumor that belongs to a group of brain tumors called "gliomas" that originate and grow in the brain and spinal cord. Classified as a grade 4 tumor by the ...
Brain Cancer Breakthrough: New Therapy Destroys Glioblastoma …
Aug 2, 2024 · A groundbreaking study introduces a therapy that uses CAR T cells to target a newly discovered cancer cell infiltration pathway in the brain, effectively doubling survival times and eradicating tumors in preclinical models.
A New Vaccine to Target Treatment-Resistant Glioblastoma
Mar 8, 2024 · In fact, the cancer completely disappeared in seven out of 10 mice who received the rWTC-MBTA vaccine three times a week for four weeks. The vaccine even extended survival in a specific mouse model of glioblastoma that is highly resistant to immunotherapy.
Preliminary Clinical Trial Results Show ‘Dramatic and Rapid’ …
The trial, known as INCIPIENT, is designed to evaluate the safety of CARv3-TEAM-E T cells in patients with recurrent GBM. Just days after a single treatment, patients experienced dramatic reductions in their tumors, with one patient achieving near-complete tumor regression.
mRNA Vaccine Boosts Immune Response Against Glioblastoma
Jun 11, 2024 · A nanoparticle-based mRNA vaccine improved survival in dogs with brain cancer and induced rapid immune responses in a small study in humans with glioblastoma.