This study corroborates recent findings from another group and provides valuable insights into the structure of the autophagy initiation complex, which includes ULK1, ATG13, and FIP200. The authors ...
In mammals, autophagosome formation, a central event in autophagy, is initiated by the ULK complex comprising ULK1/2, FIP200, ATG13, and ATG101. However, the structural basis and mechanism of the ULK ...