The San Francisco 49ers face division rivals the Arizona Cardinals at 1:05 p.m. PDT on Sunday, Oct. 6 at Levi’s Stadium in ...

The 49ers must overcome not only temperatures in the 90s but do so against an Arizona team with offensive firepower.

Kyler Murray and the Arizona Cardinals (1-3) have not been consistent and are banged up on the offensive line, but they have ...

It’s Week 5, folks! Time to set those fantasy lineups! Start ‘Em, Sit 'Em is the ultimate look at the best and worst matchups in a given week for fantasy footba ...

The league rejected the Niners and they will have to wear the darker uniforms despite the heat wave. Head coach Kyle Shanahan ...

Depending on your spiritual bent, you may have been either thrilled or turned off by San Francisco 49ers quarterback Brock ...

When asked about his teammate Brandon Aiyuk, San Francisco 49ers QB Brock Purdy didn't hesitate to speak openly about his ...

WR Deebo Samuel Sr., TE George Kittle, S Talanoa Hufanga and LB Dee Winters detailed their scouting report on the Cardinals, ...

San Francisco's defense rebounded against the Patriots but faces a tougher test in Murray's dynamic playmaking ability. Brock ...

Brock Purdy is having the best season of his career, but his numbers are down and his record is 2-2. He's having to work ...

The San Francisco 49ers will likely be active ahead of the Nov. 5 NFL trade deadline. Don't expect general manager John Lynch ...

Kyle Kempt's days in Massillon were a distant memory when he was a third-string junior college QB. He was destined for the ...