Researchers in the U.K. have succeeded in reverse engineering the defective cryptic splicing that drives amyotrophic lateral ...

The study, published this week in Nature Genetics, shows that the biggest impact of alternative splicing may come via its role in regulating gene expression levels. The research team, led by Yang Li, ...

The Nobel Assembly at Sweden's Karolinska Institutet awarded the 2024 Nobel Prize in Physiology or Medicine jointly to ...

Nobel Prize in Medicine awarded to US scientists for groundbreaking discovery in microRNA, unlocking new possibilities for ...

U1 snRNP interactions in Arabidopsis highlight its dual role in splicing and mRNA regulation, essential for maintaining transcript integrity and growth.

Nobel Prize in Physiology or Medicine was awarded jointly to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in regulation.

Victor Ambros and Gary Ruvkun win 2024 Nobel Prize for their groundbreaking discovery of microRNA's role. Recognised by ...

Variants in a gene that plays a key role in heart function can cause potentially life-threatening arrhythmia syndromes known ...

Gene regulation refers to the mechanisms that ... increasingly sophisticated omics data and computational models of the splicing code are paving the way to more accurate, context-specific splicing ...

Shrews evolved high heart rates by losing protein regulation. This discovery could help human heart treatments.

a high-throughput assay to annotate the effect of germline variants on RNA-splicing. They calibrate the assay and deploy it to study hundreds of variants in the arrhythmia-associated gene SCN5A.

The Nobel Prize for Physiology or Medicine has been awarded to Victor Ambros ( University of Massachusetts Medical School) and Gary Ruvkun ( Harvard Medical School [HMS], both MA, USA) for their ...