Isère is a landlocked department in the southeastern French region of Auvergne-Rhône-Alpes. Named after the river Isère, it had a populati…Isère is a landlocked department in the southeastern French region of Auvergne-Rhône-Alpes. Named after the river Isère, it had a population of 1,271,166 in 2019. Its prefecture is Grenoble. It borders Rhône to the northwest, Ain to the north, Savoie to the east, Hautes-Alpes to the south, Drôme and Ardèche to the southwest and Loire to the west.
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