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WEBeLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that encourages and recognises the most responsible behaviours in …
Latest research | eLife
WEBSep 3, 2024 — eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that encourages and recognises the most responsible behaviours in science. eLife Sciences Publications, Ltd is a limited liability non-profit non-stock corporation incorporated in the State of Delaware ...
How to measure and evaluate binding affinities | eLife
WEBAug 6, 2020 — Quantitative measurements of biomolecule associations are central to biological understanding and are needed to build and test predictive and mechanistic models. Given the advances in high-throughput technologies and the projected increase in the availability of binding data, we found it especially timely to evaluate the current standards for ...
The Natural History of Model Organisms: The secret lives of
WEBJun 4, 2015 — Drosophila: D. hydei (the larger, dark flies) and D. melanogaster and D. simulans (the smaller, lighter flies) interacting at a food source. Although there is little sexual dimorphism between males and females of the D. hydei species, males can be distinguished in the video because they approach other flies to court. In the D. melanogaster and D. simulans species, males are smaller than the ...
Cell Division: How centrioles acquire the ability to reproduce
WEBMar 8, 2017 — Centrioles are organelles that have two critical functions. In dividing cells, they recruit a collection of proteins (known as pericentriolar material) to form larger organelles called centrosomes that nucleate microtubules and organize the spindle poles during cell division (Fu et al., 2015; Figure 1A) In non-dividing cells, centrioles are involved in the production of cilia, the tiny hair ...
Evolution of multicellularity by collective integration of spatial ...
WEBOct 16, 2020 — Abstract. At the origin of multicellularity, cells may have evolved aggregation in response to predation, for functional specialisation or to allow large-scale integration of environmental cues. These group-level properties emerged from the interactions between cells in a group, and determined the selection pressures experienced by these cells.
Research Articles - eLife
WEB2 days ago — eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that encourages and recognises the most responsible behaviours in science. eLife Sciences Publications, Ltd is a limited liability non-profit non-stock corporation incorporated in the State of Delaware ...
Publishing and peer review at eLife · eLife
WEB2 Peer review. eLife editors - who are all active researchers - discuss new submissions and decide which will be peer reviewed. The criteria used by the editors are discussed in “How and why eLife selects papers for peer review”.. Each peer reviewer is asked to write a Public Review of the article, and to recommend ways in which the authors could improve it.
Magazine - eLife
WEBeLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that encourages and recognises the most responsible behaviours in science. eLife Sciences Publications, Ltd is a limited liability non-profit non-stock corporation incorporated in the State of Delaware ...
Reliable protein-protein docking with AlphaFold, Rosetta, and …
WEBFeb 9, 2024 — Introduction. In-silico protein structure prediction, i.e., sequence to structure, tackles one of the core questions in structural biology. AlphaFold 3 has brought a paradigm shift in the field of structural biology by intertwining deep-learning (DL) tools with evolutionary data to predict single-chain structures with high accuracy. Further, AlphaFold-multimer 4 (AFm) and related work 5,6 have ...